Q:

What is Jansen disease?

waelhammad
Save to bookmark
|
2022-11-19
|
  80 
0

A 54-year-old female presents with drowsiness to the emergency. Her BP is 140/90 mm of Hg with pulse after rate 100/minute. Her investigations reveals serum creatinine 2.4 mg/dL, Na 140 mEq/L, K 4.3 mEq/L. Complete blood count (CBC) and liver function test (LFT) is normal. CT scan head is normal. Her past evaluation reveals a cervical lymph node fine needle aspiration cytology (FNAC) suggestive of granulomatous inflammation. Her bone marrow examination is suggestive of non-Hodgkin’s lymphoma.

What is Jansen disease?

Medicine, textbook solutions, Medicine textbook-solutions,
login and add your own answer to this question

All Answers

waelhammad
2022-11-19
need an explanation for this answer? contact us directly to get an explanation for this answer

This is an autosomal dominant condition resulting from constitutive receptor functioning. It occurs due to mutations in PTH1R. ↑Ca, ↓Phosphate,

↓PTH is seen.

Short-limbed dwarfism occurs due to abnormal regulation of bone growth plate. Multiple cystic resorptive areas in bone occur, similar to those seen in severe primary hyperparathyroidism.

need an explanation for this answer? contact us directly to get an explanation for this answer

total answers (1)

Similar questions

need a help?

find thousands of online teachers now