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What are the manifestations of hypercalcemia?

waelhammad
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2022-11-19
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A 54-year-old female presents with drowsiness to the emergency. Her BP is 140/90 mm of Hg with pulse after rate 100/minute. Her investigations reveals serum creatinine 2.4 mg/dL, Na 140 mEq/L, K 4.3 mEq/L. Complete blood count (CBC) and liver function test (LFT) is normal. CT scan head is normal. Her past evaluation reveals a cervical lymph node fine needle aspiration cytology (FNAC) suggestive of granulomatous inflammation. Her bone marrow examination is suggestive of non-Hodgkin’s lymphoma.

What are the manifestations of hypercalcemia?

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waelhammad
2022-11-19
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• Gastrointestinal (GI)—anorexia, nausea, vomiting, gastroesophageal-reflux disease (GERD), peptic ulcer, acute pancreatitis.

• Renal—polyuria (decreased urinary concentrating ability), nephrocalcinosis, nephrolithiasis.

• Cardiovascular system (CVS)—hypertension, bradycardia, shortened QT interval on ECG.

• Central nervous system (CNS)—weakness, fatigue, lassitude, depression, confusion, stupor, coma.

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