Q:

What hormone therapy should be offered to this patient?

waelhammad
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2022-11-19
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A girl is brought at the age of 17 years with complaints of primary amenorrhea. She is born at full term with no perinatal complications and her motor and sensory milestones are normal. She is 165 cm in height and her predicted height is 155 cm. On examination she has B3 staging of breast with absence of axillary and pubic hairs. Her serum E2 level is low and her FSH and LH are high. Her serum testosterone is 1000 ng/mL and her USG pelvis does not show any uterus or ovaries. She has a blind vaginal pouch on vaginal examination by the gynecologist.

What hormone therapy should be offered to this patient?

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waelhammad
2022-11-19
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The patient first needs to be counseled and after patient’s consent first mgonadectomy has to be done and the patient has to be continued on adult dose of estrogens. If the gonadectomy is performed before puberty for some reason the puberty induction protocol for estrogen therapy has to be followed.

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