Q:

What is primary amenorrhea?

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A girl is brought at the age of 17 years with complaints of primary amenorrhea. She is born at full term with no perinatal complications and her motor and sensory milestones are normal. She is 165 cm in height and her predicted height is 155 cm. On examination she has B3 staging of breast with absence of axillary and pubic hairs. Her serum E2 level is low and her FSH and LH are high. Her serum testosterone is 1000 ng/mL and her USG pelvis does not show any uterus or ovaries. She has a blind vaginal pouch on vaginal examination by the gynecologist.

What is primary amenorrhea?

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Primary amenorrhea is defined as the absence of menses at age 15 years in the presence of normal growth and secondary sexual characteristics. Some authorities recommend evaluating a girl for primary amenorrhea if her menses have not occurred by age 15 years. If no menses have occurred and there is an absence of secondary sexual characteristics, such as breast development, evaluation for primary amenorrhea should be done at the age of 13 years (Flowchart 14.1).

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