Q:

What is the principle of the uptake study?

0

A 30-year-old woman presents with complaints of palpitations, tremulousness and weight loss of around 4 kg (despite a good appetite) over the last 2 months. On examination, she is anxious, has a pulse rate of 100/min, warm and moist peripheries, fine tremors of the outstretched hands and a visible goiter. No obvious abnormalities in the eyes. Her last menstrual period was 15 days ago. Her primary care physician orders for laboratory examination which reveals normal hemogram with an erythrocyte sedimentation rate of 25 mm in the first hour. Thyroid stimulating hormone (TSH) <0.001 mIU/L and total T4 28 mg/dL. A diagnosis of thyrotoxicosis is made. She is started on beta-blockers and she is asked to get a technetium uptake scan and review.

What is the principle of the uptake study?

All Answers

need an explanation for this answer? contact us directly to get an explanation for this answer

A radioactive iodine uptake (RAIU) is indicated when the diagnosis is in question. If the thyroid gland is hyperactive, then the uptake of radioiodine is elevated (like in Graves’ and toxic multinodular goiter). Whereas in conditions like thyroiditis, the uptake is close to zero. Amongst conditions with increased uptake, the pattern of uptake (in a scan study) will help differentiate. The pattern of RAIU in GD is diffuse, unless there are coexistent nodules or fibrosis. The pattern of uptake in a patient with a single TA generally shows focal uptake in the adenoma with suppressed uptake in the surrounding and contralateral thyroid tissue. The image in TMNG demonstrates multiple areas of focal increased and suppressed uptake.

need an explanation for this answer? contact us directly to get an explanation for this answer

total answers (1)

Similar questions


need a help?


find thousands of online teachers now