Q:

What investigations would you like to do to confirm your diagnosis?

0

A 29-year-old female presented with progressive swelling over the body, weight gain, menstrual irregularity. On examination, her BP was 160/100 mm Hg, pulse rate 86/min, weight 88 kg, height 155 cm. Buffalo hump was present with broad purplish striae over the abdomen. Proximal muscle weakness was present. Her investigations revealed Hb 12.6 g%, fasting blood sugar (FBS) 170 mg%, creatinine 0.9, Na 140 mEq/L, K 3.4 mEq/L (Fig. 2.1).

What investigations would you like to do to confirm your diagnosis?

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Two days low dose dexamethasone suppression test is used for diagnosis. Other tests which are supportively used for diagnosis include 24-hour urine free cortisol, midnight cortisol, salivary cortisol (Box 2.1).

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