A woman 31 years of age who is a follow-up case of acromegaly comes to the endocrinology outpatient department for follow-up. She was operated about 5 years back after which she was subjected to radiotherapy because of the residual lesion and persistently high postoperative growth hormone levels of 10 ng/mL and high levels of IGF-1. She is now four years post-radiotherapy and has come for follow-up. She has IGF-1 levels of and post-glucose growth hormone levels of 5 ng/mL. She has regular menstrual cycles and has got married. She wants to now plan for pregnancy and wants an opinion, if she can go ahead. She has a cycle with intermenstrual distance of 30 days and her 23rd day’s progesterone levels are 0.1 ng/mL. What should she be advised now?
What should be done in pregnancy?
The biochemical monitoring with GH levels and IGF-1 levels is of limited use in pregnancy.
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