A 45-year-old lady presents with complaints of a progressive increase in the size of hands and feet and shoe size for past 5 years. The family members have noticed a change in her facial appearance in the form of coarsening of features and her voice has become sonorous. She also has complaints of frequent headaches for past 1 year. She complains of amenorrhea for past 5 years. She also has complaints of joint pains for past 3 years which have become more severe for the past 3 months. She is hypertensive for past 1 year and complaints of grade 2 dyspnea on exertion and her hypertension is controlled on 10 mg of cilnidipine and 40 mg of telmisartan. She is not a known diabetic and has checked her random sugars 1 week back which was normal. She is not on any other medications presently (Fig. 1.1).
Is there any use of doing a growth hormone (GH) suppression tests?
A serum GH level after an oral glucose of 75 g anhydrous can be done, and if the levels measured every 30 minutes for 120 minutes and are less than 1 mg/L, it rules out acromegaly and a level of less than 0.4 ng/mL with ultrasensitive assays.
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