0
A 58-year-old man presen ts with generalized erythroderma with associated pruritis. weigh t loss . and cold intolerance. In addition to the generalized skin changes. he has generalized lymphadenopathy and hyperkeratosis of the palms and soles on physical exam. Com plete blood count shows leukocyte count of 22. 300/,LLL. hemoglobin 1 2 .6 g/dl. and platelet count 1 6LJ .OOO/pl. Peripheral blood smear is shown below.
Which finding is not included in making a diagnosis of SS?
- Clonal TCR rearrangement in the peripheral blood
- More than 1,000/ ,LLL Sezary cells in the peripheral blood
- 8O% skin involvement with erythroderma
- CDS positivity on immunophenotyping of a skin biopsy sample
Medicine
D. Most patients with SS express CD4, although rare patients with SS are CDS+. The other three choices represent criteria used for the diagnosis of SS (Blood. 2007;1 10:1713).
need an explanation for this answer? contact us directly to get an explanation for this answer