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A 76-year-old Female patient is referred to hematology clinic For evalua tion of persis-ten t monocytosis. CBC reveals leukocyte count of 9. 600/ JLL with absolu te monocyte count 1 200/JLL, hemoglobin 1 1 . 3 g/dl. MCV 88 FL. and pla telet count 257,000/JLL.Physical exam is normal. The peripheral blood smear is shown below.
What finding involving the white blood cell counts is common post splenectomy?
- Decreased eosinophils
- Decreased neutrophils
- Increased lymphocytes
- Decreased lymphocytes
Medicine
C. The lymphocyte count is commonly increased following splenectomy, and some patients have even been suspected of harboring a lymphoproliferative disorder, such as lymphocytic leukemia (CLL), after splenectomy. However, flow cytometry of the lymphocytes post splenectomy are poly-clonal, whereas in CLL, they are monoclonal.
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