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A 7 3-year-old man with anemia requiring transfusions for the past 3 mon ths presen ts for further evaluation . Leukocyte count is LJ ,900/ Jil, hemoglobin 7.9 g/dl, MCV 99 fl. platelet count 1 76,000/ Jil, and reticu locyte production index 0. 1 %. LDH is 1 82 U/L. On physical exam, he has no hepatosplenomegaly or lymphadenopathy. The peripheral blood smear is shown below.
What statement accurately describes the incidence and response to resection between PRCA and thymoma?
- The incidence of thymoma in patients with PRCA is near 30%, and resection leads to remission in 70% of patients.
- The incidence of thymoma in patients with PRCA is near 5%, and resection leads to remission in 70% of patients.
- The incidence of thymoma in patients with PRCA is 5% to 1 5%, and resection leads to remission in less than 40% of patients.
- The incidence of thymoma in patients with PRCA is 5% to 15%, and resection leads to remission in more than 90% of patients.
Medicine
C. Although the association between thymoma and PRCA is well recognized, the actua incidence of thymoma as a causative mechanism is low, and modern series suggest that the effect of resection of thymoma on the course of PRCA is not as beneficial as previously thought.
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