Q:

Which test is not used to confirm the diagnosis of ehrlichiosis/anaplasmosis?

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A LJ6-year-old man with a h istory of non-Hodgkin lymphoma presents with myalgias. fever. and headache. Cen tral nervous symptoms worsened, and he became seriously ill and was admitted to the in tensive care unit for eval uation and treatment. Of note. the patien t stated he had been working in the woods and though t he may have had a tick bite. He last received treatment for lymphoma 2 years previously. Laboratory shows a leukocyte count of 3 ,200/pl, hemoglobi n 1 2 .3 g/dl, and platelet count LJ 7, 000/pl. An image from the peri pheral blood smear is shown below.

Which test is not used to confirm the diagnosis of ehrlichiosis/anaplasmosis?


  1. Indirect fluorescent antibody testing
  2. PCR
  3. Cell culture
  4. Enzyme-linked immunosorbent assay

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C. Culture of erhlichiae organisms has been rarely successful. The other listed choices are all used to confirm the diagnosis.

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