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A 1 8-year-old female patien t of I ranian descent presen ts to the emergency room with back and leg pain. Laboratory results reveal leukocyte count of 1 7 , LJOO/,uL. hemoglo-bin of 1 1 . 5 g/d L, MCV of 65 FL. and platelet count of 2 97.000/,uL. Peripheral smear is shown below.
Hydroxyurea should not be used in which of the following populations?
- Children
- Patients with autoimmune conditions
- Women of child-bearing age who are not using birth control
- Patients with congestive heart failure
Medicine
C. Based on animal studies, there is significant concern about possible harm to the develop-ing fetus. Close attention to this issue prior to and throughout treatment with hydroxyurea is recom-mended (New Eng J Med. 2008;358(13): 1362-1369).
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