What is the most common structural chromosomal abnormality seen in cases of LPL?

A 5 6-year-old female presen ts For evaluation of malaise and a recent uninten tional 1 0-pound weight loss. Patien t reports no nigh t sweats or Fevers. but reports enlarged lymph nodes in her neck area. She also men tions several weeks of epistaxis and blurry vision. Physical exami nation con firms cervical lymphadenopathy and splenomegaly, and petech iae i nvolvi ng both lower extremi ties. Fundoscopic exam shows retinal hemorrhages and engorged retinal veins. Laboratory evaluation shows leukocytes of 1 2 . 700/pL hemoglobin of 1 0.8 g/dl, and platelet count of 1 78.000/JLL. Peri pheral slide is shown below.

Bone marrow biopsy is obtai ned and shows a hypercellular bone marrow with diffuse i nvolvemen t by small lymphocytes as shown below. Flow cytometry revealed positivity For CD 1 9 , CD20. and CD 1 38. with negative expression of CDS and CD2 3.

What is the most common structural chromosomal abnormality seen in cases of LPL?