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A LJ8-year-old male presen ts to the emergency room for further evaluation of a 3-week history of progressively worsening Fatigue. Physical examination reveals pal lor and dif-Fuse petech iae over lower extremities. Laboratory evaluation shows a total leukocyte cou nt of 2 3, LJOO/,uL. hemoglobin 9.8 g/dl. and platelet count of 1 3, 000/,uL. Periph-eral blood smear and bone marrow aspirate are shown.
What is the typical flow cytometry pattern of an AML?
- CD13+, CD33-, CD34-, HLD-DR+
- CD13+, CD33+, CD34+, HLD-DR+
- CD1 3-, CD33+, CD34-, HLD-DR-
- CD13-, CD33-, CD34-, HLD-DR+
- CD1 3+, CD33+, CD34-, HLD-DR+
Medicine
B. The typical flow cytometry pattern of AML includes positivity for CD13, CD33, CD34, and HLA-DR. APL is typically negative for CD34 and HLD-DR, which can serve as a quick and simple diagnostic tool (Arch Pathol Lab Med. 2003;127(1):42, Blood. 2008;111(8):3941).
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