Q:

A newborn presents with midfacial and mandibular hypoplasia, defects of the first pharyngeal arch consistent with the diagno- sis of Treacher Collins syndrome. What structure would most likely be involved with the syndrome?

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A newborn presents with midfacial and mandibular hypoplasia, defects of the first pharyngeal arch consistent with the diagno-sis of Treacher Collins syndrome. What structure would most likely be involved with the syndrome?


  1. Hyoid bone
  2. Stapes
  3. Malleus
  4. Thyroid gland
  5. Inferior parathyroid gland

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C. The malleus is the only structure on this list derived from the neural crest of the first pharyngeal arch.

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