Concerning the model of limb morphogenesis in the amphibian, Xenopus:
- degradation of collagen allows mesenchymal filopodia to contact the basal lamina of the epithelium
- contact between the mesenchymal cell surface and the epithelial basal lamina may mediate intercellular signals having morphogenetic significance; i.e., positional information
- development of low resistance pathways may functionally integrate the mesenchyme and coordinate cell division and changes in three dimensional positions
- during development, epithelial desmosomes remain stable
- all of the above (A-D)
E. all of the above (A-D)
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