Q:

A 48 year old patient after surgical removal of mandibular carcinoma presents with perioral paresthesia and severe pain which is not relieved by oral morphine. What is the next step in treating this patient?

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A 48 year old patient after surgical removal of mandibular carcinoma presents with perioral paresthesia and severe pain which is not relieved by oral morphine. What is the next step in treating this patient?


  1. Oral amitryptiline (2nd line)
  2. Oral oxycodone
  3. PCA
  4. IV morphine
  5. Fentanyl patch
  6. Gabapentine (1st line)

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The key is F. Gabapentine. [This pain is likely due to nerve injury during operation and both amitryptilin and Gabapentine are 1st line for neuropathic pain].

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