Q:

A patient who was previously on 120mg slow release oral morphine has had his dose increased to 200mg. He is still in significant pain. He complains of drowsiness and constipation. What is the next step in the management?

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A patient who was previously on 120mg slow release oral morphine has had his dose increased to 200mg. He is still in significant pain. He complains of drowsiness and constipation. What is the next step in the management?


  1. Increase slow release morphine dose
  2. Fentanyl patch
  3. Replace morphine with oral hydromorphone
  4. Replace morphine with oxycodone
  5. Subcutaneous morphine

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The key is D. Replace morphine with oxycodone.

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