Q:

A pregnant woman presents with knee pain on movements. The pain becomes worse at the end of the day. Radiology shows decreased joint space. Laboratory investigation: CRP=12. What is the 1st line medicine?

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A pregnant woman presents with knee pain on movements. The pain becomes worse at the end of the day. Radiology shows decreased joint space. Laboratory investigation: CRP=12. What is the 1st line medicine?


  1. Paracetamol
  2. NSAIDs
  3. Oral steroid
  4. Intra articular steroid
  5. DMARDs

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The key is A. Paracetamol. [Pain on movement, pain worse at end of day and decreased joint space are characteristic of osteoarthritis supported by NO significant raise in inflammatory marker (CRP=12). 1st line medicine is paracetamol].

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