A 25 year old male who recently noticed change in his shoe size, he is also constipated, has a preference to hot weather, his skin is dry, has severe pain in wrist joint. Joint is red and swollen. What is the most probable diagnosis?

The key is D. Pseudogout. [Hypothyroidism (change of shoe size due to myxedema (or pedal oedema can be seen in hypothyroidism) , other features of constipation, cold intolerance, dry skin are well known features of hypothyroidism.) has well recognized association with pseudogout].