Q:

A 6 year old girl is being investigated for renal failure. She is found to have a congenital abnormality of the insertion of the ureters into the urinary bladder. What is the single most likely cause for renal failure in this patient?

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A 6 year old girl is being investigated for renal failure. She is found to have a congenital abnormality of the insertion of the ureters into the urinary bladder. What is the single most likely cause for renal failure in this patient?


  1. SLE
  2. PKD
  3. Wilm’s tumor
  4. Acute tubular necrosis
  5. Reflux nephropathy

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The key is E. Reflux nephropathy. [Reflux nephropathy is kidney damage (nephropathy) due to urine flowing backward (reflux) from the bladder toward the kidneys; the latter is called vesicoureteral reflux (VUR)].

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