Q:

At birth, a baby boy at 38 weeks GA (gestational age) weighs 1.8kgs. He has hepato- splenomegaly and a rash. Blood test show raised level of bilirubin and liver enzymes. What is the most likely diagnosis?

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At birth, a baby boy at 38 weeks GA (gestational age) weighs 1.8kgs. He has hepato- splenomegaly and a rash. Blood test show raised level of bilirubin and liver enzymes. What is the most likely diagnosis?


  1. Galactosemia
  2. Biliary atresia
  3. G6PD deficiency
  4. Rh incompatibility
  5. Congenital viral infection

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The key is E. Congenital viral infection. [Congenital infections affect the unborn fetus or newborn infant. They are generally caused by viruses that may be picked up by the baby at any time during the pregnancy up through the time of delivery. The more common viruses linked to congenital infections include the Cytomegalovirus (CMV), Herpes, Rubella (German measles), Parvovirus, Varicella (chickenpox), and Enteroviruses].

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