Q:

A 12 month old child with AIDS is due for his MMR vaccination. What is the single most appropriate action?

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A 12 month old child with AIDS is due for his MMR vaccination. What is the single most appropriate action?


  1. Defer immunization for 2wks
  2. Don’t give vaccine
  3. Give half dose of vaccine
  4. Give paracetamol with future doses of the same vaccine
  5. Proceed with standard immunization schedule

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The key is B. Don’t give vaccine. [MMR is live attenuated vaccine which should be avoided in AIDS]. [*** Please note, in similar question where asked about HIV positive child’s vaccination and the answer was give all vaccines except BCG. HIV positive is not in a immunodeficient state and can receive live attenuated vaccines (except BCG), where as child with AIDS means he has criteria of immunodeficiency already for which all live attenuated vaccines should be avoided]. [Please note the two terms “HIV positive” and “with AIDS”].

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