Q:

A 3 year old child who looks wasted on examination has a history of diarrhea on and off. The mother describes the stool as bulky, frothy and difficult to flush. What is the single investigation most likely to lead to diagnosis?

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A 3 year old child who looks wasted on examination has a history of diarrhea on and off. The mother describes the stool as bulky, frothy and difficult to flush. What is the single investigation most likely to lead to diagnosis?


  1. Sweat chloride test
  2. Anti-endomysial antibodies
  3. LFT
  4. US abdomen
  5. TFT

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The key is B. Anti-endomysial antibody. [The diagnosis is celiac disease. It is not cystic fibrosis as lung problem is most commonly seen in cystic fibrosis along with GI problem like indigestion].

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