A woman with sickle cell disease complains of heavy menstrual blood loss. What is the most appropriate treatment?

The key is C. Depot provera. [Hormone and barrier methods are all acceptable choices but intrauterine devices are not recommended, as they may be associated with uterine bleeding and infection. Depot contraceptive (Depo-Provera) is safe and has been found to improve the blood picture and reduce pain crises. Source: patient.info].