Q:

A 24 year old lady with BMI 30 complains of facial hair growth and history of amenorrhea. FSH 10.9, prolactin=400IU, estradiol 177.8mmol/l, progesterone normal, LH 33.2. What is the most probable diagnosis?

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A 24 year old lady with BMI 30 complains of facial hair growth and history of amenorrhea. FSH 10.9, prolactin=400IU, estradiol 177.8mmol/l, progesterone normal, LH 33.2. What is the most probable diagnosis?


  1. PCOS
  2. Pregnancy
  3. Cushing’s disease
  4. CAH
  5. POF

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The key is A. PCOS. [Clinical features (obesity, hirsutism, amenorrhea etc.) are consistent with PCOS. We know in PCOS LH:FSH ratio is 2:1 or 3:1. Here LH is 33.2 and FSH is 10.9 which also supports diagnosis of PCOS].

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