Q:

Patient with a long history of smoking is now suffering from bronchial carcinoma. Histology reveals there are sheets of large polygonal or giant MNC (multineucleated cells). What is the most likely diagnosis?

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Patient with a long history of smoking is now suffering from bronchial carcinoma. Histology reveals there are sheets of large polygonal or giant MNC (multineucleated cells). What is the most likely diagnosis?


  1. Squamous cell ca
  2. Small cell ca
  3. Adenocarcinoma
  4. Large cell ca
  5. Oat cell ca

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The key is D. Large cell ca. [Large cell carcinoma is, by definition, a poorly differentiated malignant epithelial tumor. It consists of sheets or nests of large polygonal or giant multinuclear cells and probably represents SCC ."]

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