Q:

A 68 year old man has had increasing dysphagia for solid food for 3 months and has lost 5kgs in weight. What single investigation is most likely to lead to a definitive diagnosis?

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A 68 year old man has had increasing dysphagia for solid food for 3 months and has lost 5kgs in weight. What single investigation is most likely to lead to a definitive diagnosis?


  1. Barium swallow
  2. CXR
  3. CT chest
  4. Endoscopy and biopsy
  5. Video-fluoroscopy

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The key is D. Endoscopy and biopsy. [Likely cause is malignant stricture for which endoscopic biopsy is the definitive investigation].

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