Q:

A 40 year old man with a 25 year history of smoking presents with progressive hoarseness of voice, difficulty swallowing and episodes of hemoptysis. He mentioned that he used to be a regular cannabis user. What is the single most likely diagnosis?

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A 40 year old man with a 25 year history of smoking presents with progressive hoarseness of voice, difficulty swallowing and episodes of hemoptysis. He mentioned that he used to be a regular cannabis user. What is the single most likely diagnosis?


  1. Nasopharyngeal cancer
  2. Pharyngeal carcinoma
  3. Sinus squamous cell carcinoma
  4. Squamous cell laryngeal cancer
  5. Hypopharyngeal tumor

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The key is D. Squamous cell laryngeal cancer.

• Chronic hoarseness is the most common early symptom.

• Other symptoms of laryngeal cancer include pain, dysphagia, a lump in the neck, sore throat,

earache or a persistent cough.

• Patients may also describe breathlessness, aspiration, haemoptysis, fatigue and weakness, or

weight loss. (Patient.co.uk)

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