Q:

A 60 year old man has a pathological rib fracture. He also complains of recurrent infection. BMA (bone marrow aspiration) is done. Labs: Ca2+ 3.9mmol/L and ALP 127u/L. what type of cell would be found in abdundance in the marrow smear?

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A 60 year old man has a pathological rib fracture. He also complains of recurrent infection. BMA (bone marrow aspiration) is done. Labs: Ca2+ 3.9mmol/L and ALP 127u/L. what type of cell would be found in abdundance in the marrow smear?


  1. Plasma cell
  2. Myeloid cell
  3. Bence-jones protein
  4. Megakaryocytes
  5. Reticulocytes

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The key is A. Plasma cell. [The diagnosis of multiple myeloma. i) age 60 yrs ii) pathological rib fracture (from metastases) iii) recurrent infection (due to B cell dysfunction (manifested as hypogammaglobulinemia), numerical and functional abnormalities of T cells, and dysfunction of natural killer cells), iv) raised calcium level.

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