Q:

An old man having T2DM with increased skin tanning, heart failure and having high ferritin (hemochromatosis) level is refusing treatment. Where is the first site of cancer?

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An old man having T2DM with increased skin tanning, heart failure and having high ferritin (hemochromatosis) level is refusing treatment. Where is the first site of cancer?


  1. Testes
  2. Adrenal
  3. Liver
  4. Pancreas

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The key is C. Liver. [Diagnosis is hemochromatosis. Hemochromatosis is the abnormal accumulation of iron in parenchymal organs, leading to organ toxicity. It is the most common autosomal recessive genetic disorder and the most common cause of severe iron overload leading to hepatomegaly, liver cirrhosis and liver cancer, hyperpigmentation, diabetes mellitus, arthropathy, cardiomyopathy etc.].

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