Q:

An 8 year old child who is tall for his age and has a refractory error for which he wears glasses has presented with severe crushing chest pain. What is the most likely diagnosis?

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An 8 year old child who is tall for his age and has a refractory error for which he wears glasses has presented with severe crushing chest pain. What is the most likely diagnosis?


  1. Fragile X syndrome
  2. Prader-willi syndrome
  3. DiGeorge syndrome
  4. Marfans syndrome

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The key is D. Marfans syndrome. [Cause of severe crushing chest pain may be aortic dissection or angina. Most common cardiac abnormalities in Marfans syndrome are: dilatation of the aorta and mitral regurgitation. Other features are tall and thin stature, with long arms, legs, fingers and toes. They also typically have flexible joints and scoliosis. There may be partial lens dislocation, where the lens is shifted out of its normal position].

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