This condition affects middle aged women more than men and is characterized by low mood, early morning waking, loss of libido, tiredness and suicidal intention last for at least 2wks. What is the most probable diagnosis?

The key is C. Major depressive disorder. [Given case is severe depression (major depressive disorder).

• Mild depression: i)Low mood ii) Anhedonia iii) Guilt iv) Hopelessness v) Worthlessness vi) Inability to concentrate. Treatment CBT

• Moderate depression: Features of mild + vii) Poor sleep viii) Poor Appetite ix) Poor libido x) Easy fatiguability. Treatment Antidepressants

• Severe depression: Features of moderate + xi) Suicidal intensions. Treatment ECT

• Psychotic depression: Features of severe + xii) Hallucinations xiii) Delusions xiv) Guilt xv)