Q:

A man on antipsychotic medicines develops features of retinitis pigmentosa. Which drug is most likely to cause these symptoms?

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A man on antipsychotic medicines develops features of retinitis pigmentosa. Which drug is most likely to cause these symptoms?


  1. Thioridazine
  2. Haloperidol
  3. Chlorpromazine
  4. Risperidone

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The key is A. Thioridazine. [Thioridazine and other antipsychotics (neuroleptics, dopaminergic antagonists) can cause degenerative retinopathies with histological, electrophysiological and symptomatological features similar to those of primary retinitis pigmentosa].

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