Q:

A 35 year old woman has butterfly rash on her face and she suffers symmetrical joint pains on knee and elbow, ESR is raised. What is the most discriminative investigation for diagnosis?

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A 35 year old woman has butterfly rash on her face and she suffers symmetrical joint pains on knee and elbow, ESR is raised. What is the most discriminative investigation for diagnosis?


  1. Anti DNA antibodies
  2. Anti Jo1 antibodies
  3. Anti nuclear antibodies
  4. Anti centromere antibodies
  5. Anti la antibodies

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The key is A. Anti DNA antibodies. [Anti DNA antibodies to diagnose SLE].

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