Q:

A 46 year old male presents with confusion and drowsiness. What is the most likely diagnosis?

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A 46 year old male presents with confusion and drowsiness. What is the most likely diagnosis?


  1. Cryptococcus neoformans
  2. Toxoplasma gondii
  3. HSV
  4. CMV
  5. Candida albicans

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The key is A. Cryptococcus neoformans. [This type of question can be regarded as cns infection in

AIDS and some may argue there is no mention of AIDS. If you consider with immubnocompetent patient

likely answer may be HSV and if you consider immunodeficiency likely answer is controversial! as some

say toxoplasmosis as the most common and some say Cryptococcus is most common].

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