Q:

A 34 year old man from Asia presented with 5months history of productive cough, night sweats and weight loss. His CXR reveals some shadowing in the left upper zone. What is the single most discriminating investigation?

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A 34 year old man from Asia presented with 5months history of productive cough, night sweats

and weight loss. His CXR reveals some shadowing in the left upper zone. What is the single most

discriminating investigation?


  1. AFB for sputum
  2. CXR
  3. CT
  4. TFT
  5. US abdomen

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The key is A. Sputum for AFB. [Cough, night sweats and weight loss are common features of TB.

Apical lesions in lung on chest X-ray are suggestive of PTB (pulmonary tuberculosis). Most discriminating

investigation is AFB for sputum].

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