Q:

A 45 year old man has developed an annular rash with a scaly edge on his thigh. The rash has been spreading over the last 3wks. He has some general aches and pains. What is the single most useful investigation?

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A 45 year old man has developed an annular rash with a scaly edge on his thigh. The rash has

been spreading over the last 3wks. He has some general aches and pains. What is the single

most useful investigation?


  1. ANA
  2. Biopsy lesion
  3. Lyme antibodies
  4. Skin scrap for mycology
  5. Skin swab for bacteria

All Answers

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The key is C. Lyme antibodies. [Spreading annular rash suggests erythema migrans of lyme disease].

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