Q:

A middle aged lady presented with fever, altered sensorium, bleeding gums and jaundice. Laboratory investigations: deranged renal function tests, normal PT/APTT, fragmented RBCs and low platelets. What’s the most likely dx?

waelhammad
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2022-11-01
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A middle aged lady presented with fever, altered sensorium, bleeding gums and jaundice. Laboratory investigations: deranged renal function tests, normal PT/APTT, fragmented RBCs and low platelets. What’s the most likely dx?  

  1. Cholesterol emboli
  2. HUS (hemolytic uremic syndrome)
  3. TTP (thrombotic thrombocytopenic purpura)
  4. Hepatorenal syndrome
  5. Sepsis
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waelhammad
2022-11-01
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The key is C. TTP. [Fever and altered sensorium suggest the diagnosis of TTP. Also in TTP there is fragmented RBC which is present here and low platelet counts]. 

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