A 50 year old lady has been suffering from chronic RA (rheumatoid arthritis) and is on methotraxate and naproxen. Her CBC shows microcytic anemia. What is the most likely cause?
belongs to book: 1700 MCQ REVISED VERSION TOPIC WISE|DR. KHALID SAIFULLAH|4th EDITION| Chapter number:6| Question number:26
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Medicine
The key is B. GI hemorrhage. [Anemia of chronic disease is mostly normocytic and methotrexate causes folate deficiency which may lead to macrocytosis. So for this microcytic anemia NSAIDs induced GI hemorrhage is the most likely cause].
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