A patient presents with skin pigmentation, diarrhea, vomiting, abdominal pain and postural hypotension. What electrolyte abnormality is likely to occur?
belongs to book: 1700 MCQ REVISED VERSION TOPIC WISE|DR. KHALID SAIFULLAH|4th EDITION| Chapter number:4| Question number:48
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The key is A. Na+=130, K+=6.5. [Addison disease is adrenocortical insufficiency due to the
destruction or dysfunction of the entire adrenal cortex. It affects glucocorticoid and mineralocorticoid
function. The onset of disease usually occurs when 90% or more of both adrenal cortices are
dysfunctional or destroyed. Hyperpigmentation of the skin and mucous membranes often precedes all
other symptoms by months to years. Diarrhea, vomiting, abdominal pain and postural hypotension are
well known features of acute addisons disease. In Addison’s disease there is low Na+, low Cl-, low CO2
and raised K+].
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