Q:

A 45 year old man presented to his GP with vague symptoms of headache, proximal muscle weakness and nocturia. Test results show him to be severely hypertensive (230/130mmHg) and hypokalemic. What is the most probable diagnosis?

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A 45 year old man presented to his GP with vague symptoms of headache, proximal muscle

weakness and nocturia. Test results show him to be severely hypertensive (230/130mmHg) and

hypokalemic. What is the most probable diagnosis?


  1. Addison’s disease
  2. Conn’s disease
  3. Familial hyperaldosteronism
  4. Cushing’s disease
  5. Cushing’s syndrome

All Answers

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The key is B. Conn’s disease. [High BP is often the only presentation of Conn’s syndrome. Loss of K+

in urine leads to hypokalemia which in turn causes muscle weakness and polyuria particularly nocturia].

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