Q:

A 45 year old lady complains of expressible galactorrhea, decreased libido and amenorrhea, weight gain and easy fatigue. Her serum prolactin levels are 1100um/l. what is the likely cause of hyperprolactinemia?

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A 45 year old lady complains of expressible galactorrhea, decreased libido and amenorrhea,

weight gain and easy fatigue. Her serum prolactin levels are 1100um/l. what is the likely cause

of hyperprolactinemia?


  1. Hypothyroidism
  2. Stress
  3. Pregnancy
  4. Prolactin secreting pituitary tumor
  5. PCOS

All Answers

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The key is D. Prolactin secreting pituitary tumor. This is wrong key. Correct key should be A.

Hypothyroidism. [ It is likely to be hypothyroidism because prolactin level in hypothyroidism may be 30-

200ng/ml which means 630-4200 mIU/L. Though weight gain can occur but fatigue is not a feature of

prolactinoma unless it is a macroadenoma causing suppression of other pituitary hormone! given

prolactin level of 1100 IU/L is definitely from a microadenoma (in macroadenoma prolactin level is >

10,000 MU/L) which does not cause fatigue. So the case most likely seems to be hypothyroidism].

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