Q:

A 43 year old woman has been feeling lethargic and tired. Her BP is 160/90mmHg. Bloods test: Na+ 140mmol/L, K+ 3.1mmol/L. What is the most likely diagnosis?

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A 43 year old woman has been feeling lethargic and tired. Her BP is 160/90mmHg. Bloods test:

Na+ 140mmol/L, K+ 3.1mmol/L. What is the most likely diagnosis?


  1. Cushing’s syndrome
  2. Conn’s syndrome
  3. Hyperparathyroidism
  4. Renal disease
  5. Pheochromocytoma

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The key is B. Conn’s syndrome. [Here potassium is < 3.5, sodium is at its high normal and

hypertension is present. Most likely diagnosis is conn's syndrome. Cushing's syndrome is a D/D but it

has typical clinical feature which is usually described if the question is for cushing's syndrome. It can also

be cushing’s syndrome! So if we like to be sure we have to know aldosterone and rennin level. i) Renin

 

low, aldosterone high- Conn’s syndrome (primary hyperaldosteronism) ii) Renin low, aldosterone low-

Cushing’s syndrome iii) Renin high, aldosterone high- Renovascular disease (secondary

 

hyperaldosteronism)].

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