Q:

A 29 year old woman presents to her GP with a history of weight loss, heat intolerance, poor concentration and palpitations. Which of the following is most likely to be associated with diagnosis of thyroiditis associated with viral infection?

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A 29 year old woman presents to her GP with a history of weight loss, heat intolerance, poor concentration and palpitations. Which of the following is most likely to be associated with diagnosis of thyroiditis associated with viral infection?


  1. Bilateral exophthalmos
  2. Diffuse, smooth goiter
  3. Reduced uptake on thyroid isotope scan
  4. Positive thyroid peroxidase antibodies
  5. Pretibial myxedema

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The key is C. Reduced uptake on thyroid isotope scan. [The diagnosis is De Quervain’s or subacute thyroiditis. Diagnostic criteria: i) Features of hyperthyroidism present. ii) Pain thyroid (not mentioned in given question) iii) Investigations: high esr (60-100) (not mentioned in given question) Reduced uptake of radioactive iodine by the gland].

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