Q:

A 53 year old man with previous history of COPD presents with breathlessness and purulent sputum. O2 stat 85% on air. ABG: PaO2-7.6, PaCO2-7. What is the appropriate management for his condition?

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A 53 year old man with previous history of COPD presents with breathlessness and purulent sputum. O2 stat 85% on air. ABG: PaO2-7.6, PaCO2-7. What is the appropriate management for his condition?


  1. 24% oxygen
  2. Mechanical ventilation
  3. 100% oxygen
  4. Nebulized salbutamol

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The key is A. 24% oxygen. [Patient has hypoxemia and hypercapnea (type2 respiratory failure). Hence he should be put on 24% oxygen. 100% oxygen will abolish hypoxic drive and worsen hypercapnea].

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