A 50 year old man presented with increased breathlessness at rest. He is currently on furosemide, digoxin and isosorbide mononitrate. What drug is going to help him?

The key is B. Bendroflumethiazide. [This is a case of diuretic resistance. Heart failure represents the most common clinical situation in which diuretic resistance is observed. In mild CHF, diuretic resistance is not commonly encountered, as long as renal function is preserved. However, in moderate and severe CHF patients, diuretic resistance occurs more frequently and often becomes a clinical problem. In diuretic resistance another diuretic is added to get optimal or desirable result. As patient is still in heart failure and pulmonary edema with the usage of loop diuretic...a thiazide diuretic could be added with loop when response is inadequate. This will reduce the volume overload and improve breathing].