Q:

What would happen if a neuron lost its myelin sheath?

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What would happen if a neuron lost its myelin sheath?


  1. Na + would leak out of the axon leaving too few ions to stimulate the Na channels at the next node to open.
  2. The neuron would die.
  3. More Na + channels would be exposed allowing freer entry so conduction speed would increase.
  4. More K + channels would be exposed allowing freer exit so the cell would hyperpolarise.

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A: The myelin sheath prevents sodium ions from leaking back into the intracellular fl uid hence they can travel with minimum diminution to the next node to trigger the opening of abundant voltage-gated sodium channels. 

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