Q:

Patients with diabetes mellitus who neglect insulin therapy rapidly metabolize lipids, and there may be an accumulation of the acidic by-products of lipid metabolism in the blood. What effect would this have on respiration?

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Patients with diabetes mellitus who neglect insulin therapy rapidly metabolize lipids, and there may be an accumulation of the acidic by-products of lipid metabolism in the blood. What effect would this have on respiration?


  1. increase in respiratory rate
  2. decrease in respiratory rate
  3. decrease in respiratory rate if oxygen is reduced
  4. no infl uence on respiratory rate

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A: Respiratory rate increases if blood pH decreases in order to breathe out carbon dioxide (and hence reduce acid). In uncontrolled diabetics this is known a Kussmaul breathing. 

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